Advanced Models for Target Validation & Drug Discovery in Prostate Cancer
نویسندگان
چکیده
منابع مشابه
Preclinical Remodeling of Human Prostate Cancer through the PTEN/AKT Pathway
Knowledge gained from the identification of genetic and epigenetic alterations that contribute to the progression of prostate cancer in humans is now being implemented in the development of functionally relevant translational models. GEM (genetically modified mouse) models are being developed to incorporate the same molecular defects associated with human prostate cancer. Haploinsufficiency is ...
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